Ubiquitous Smartphone Bioluminescence Detection

A simple, inexpensive, smartphone-based hardware/software solution (BAQS) dramatically increases detection sensitivity for quick, on-site environmental surveying and food safety analysis using bioluminescent probes.
Technology No. 2016-BAE-67395

Smartphone cameras have uses beyond the usual photos taken for social media apps. There are potential applications in searching for biological matter in environmental surveys and on-site food safety inspections. However, for widespread usage of smartphone-based detection, there is a bottleneck of low sensitivity associated with the sensor of a standard commercial smartphone. Other methods, such as sending actual samples to a laboratory for analysis using high sensitivity detectors, delay the results and impose economic losses in cases of food inspection.

Researchers at Purdue University have developed a smartphone-based device and image processing method to maximize the sensitivity of the typical smartphone camera. The proposed hardware/software combination, named the "Bioluminescent-based Analyte Quantitation by Smartphone (BAQS)," provides a quick, on-site method for analysis of samples tagged with a bioluminescent probe. A structure houses the smartphone, sample, and collection lens, while an algorithm lowers the signal background and enhances the signal from bioluminescent photons.

Advantages:

-Simple & inexpensive

-Achieves large increases in detection

-On-site; no delays in sending samples to labs

Potential applications:

-Environmental surveying

-Food inspection

TRL: 4

Intellectual Property:

Copyright, 2017-09-29, United States | Provisional-Patent, 2017-10-30, United States | Utility Patent, 2018-10-30, United States | CON-Gov. Funding, 2020-07-14, United States

Keywords: Smartphone detection, bioluminescent analysis, on-site diagnostics, food safety inspection, environmental surveying, analyte quantitation, low-cost detection, portable biosensor, image processing method, BAQS

  • expand_more mode_edit Authors (4)
    Bruce Applegate
    Euiwon Bae
    Youngkee Jung
    Huisung Kim
  • expand_more cloud_download Supporting documents (1)
    Product brochure
    Ubiquitous Smartphone Bioluminescence Detection.pdf
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