Application of Wireless Sensor Networks to Lyophilization for Enhanced Process Monitoring and Control

Researchers at Purdue University have developed a sensor network that monitors chamber pressure and temperature and estimates the sublimation rate of a solvent during lyophilization. The technology enables optimizing drying in real time, and unlike other methods it is non-invasive, as it does not require temperature probes to be placed into the material. The sensor network is wireless and therefore can be integrated deep into the shelf. Applications for the technology include in lyophilization of drugs and foods.

Advantages:

-Real time tunability of drying

-Non-invasive

-Wireless

Potential Applications:

-Lyophilization

TRL: 3

Intellectual Property:

Keywords: Wireless sensor network, lyophilization, sublimation rate, process monitoring, drying optimization, real time control, non-invasive sensor, chamber pressure, temperature monitoring, pharmaceutical drying