Heterogeneous Hydroxyl-Directed Hydrogenation over a Pd-M Alloy Catalyst

Currently, there are no heterogeneous catalysts available for high yielding and stereoselective hydrogenation of hydroxyl-containing substrates. Researchers at Purdue University have developed a Pd-Cu nanoparticle heterogeneous catalyst for this application that demonstrates high conversion of up to 99% with diastereoselectivity as high 17:1 for the substrates examined. Because this is a supported catalyst, this also means that it can be easily recycled. Advances in this area have applications in pharmaceuticals and specialty chemicals.

Advantages:

- More cost effective than homogeneous alternatives

- Recyclable

- Heterogeneous

Applications:

- Pharmaceuticals

- Specialty chemicals

Technology Validation:

This technology has been validated through laboratory demonstration.

TRL: 4

Intellectual Property:

Keywords: Catalyst, catalysts, Chemistry, Chemistry and Chemical Analysis, hydrogenation